Christina Applegate Reflects on Early MS Symptoms During ‘Dead to Me’ Filming

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Christina Applegate, a celebrated actress known for her exceptional talent and beloved roles, opened up about her journey with Multiple Sclerosis (MS) and how the early signs of the disease surfaced years before her diagnosis. During the filming of the pilot episode of Netflix’s award-winning series Dead to Me, Applegate unknowingly experienced symptoms of MS that she later recognized as warning signs of the autoimmune disorder. In a heartfelt conversation on her podcast, Messy, she shared these moments, revealing the resilience and support she received from her team during challenging times.

Christina Applegate Reflects on Early MS Symptoms During 'Dead to Me' Filming
Christina Applegate Reflects on Early MS Symptoms During ‘Dead to Me’ Filming

Recognizing the First Signs of MS on the Set of Dead to Me

In a conversation with her cohost Jamie-Lynn Sigler, who is also an MS patient, and her friend, Dead to Me creator Liz Feldman, Christina Applegate recalled one of the earliest signs of her condition. During a scene requiring her to run across a field, she unexpectedly fell—a moment that seemed minor at the time but now resonates deeply as a pivotal indication of her developing illness.

“I remember falling that day,” Applegate shared. “Hi, first sign of MS!” Feldman added her perspective, recounting how the long shooting hours could have made anyone feel exhausted. “It was late at night, and we had been working for hours. It seemed like a plausible reaction to fatigue, but looking back, it was something more.”

Diagnosis and the Journey to Understanding MS

Applegate was officially diagnosed with MS in 2021, more than two years after she first noticed the symptoms. During the filming of the final season of Dead to Me, she experienced persistent back pain, tingling sensations, and other indicators that pushed her to seek medical evaluation. The diagnosis came as a life-altering moment for the actress, prompting her to reassess her career and personal priorities.

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“I could sense something was wrong,” Feldman said. “Her body wasn’t responding the way she wanted it to. I reassured her many times that the show was secondary to her health.”

A Supportive Environment on Set

The cast and crew of Dead to Me went above and beyond to accommodate Applegate during her battle with MS. Scenes were adapted, schedules were adjusted, and her needs were prioritized, ensuring she could continue working comfortably.

“That kind of support doesn’t happen everywhere,” Applegate emphasized. “The humanity and love I felt from everyone on set were extraordinary. It’s not the normal reaction, and I can’t express my gratitude enough.”

Christina Applegate’s Life After MS Diagnosis

Since her diagnosis, Applegate has retired from on-camera acting but remains open to voiceover work. On her podcast, she candidly shared the daily challenges she faces due to the disease.

“I’m in pain every single day,” she revealed. “I lay in bed screaming sometimes because of the sharp pains and aches. But I keep going, thanks to my humor and the love from those around me.”

Her sense of humor, which she calls her “sick sense of humor,” has been a vital coping mechanism. It’s a testament to her indomitable spirit and ability to find light even in the darkest moments.

What is Multiple Sclerosis (MS)?

Multiple Sclerosis is a chronic autoimmune disorder that affects the central nervous system, disrupting communication between the brain and the rest of the body. Symptoms can vary widely, including fatigue, balance issues, muscle weakness, and severe pain, as experienced by Applegate. The condition has no known cure, but treatments can help manage symptoms and slow disease progression.

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Christina Applegate’s Legacy and Inspiration

Despite stepping away from acting, Christina Applegate’s story continues to inspire countless individuals. Her openness about living with MS has brought attention to the struggles faced by those with chronic illnesses and the importance of support systems in overcoming challenges.

As she reflects on her journey, Applegate remains a beacon of resilience, humor, and unwavering strength in the face of adversity.

FAQs About Christina Applegate and MS

1. When did Christina Applegate first notice symptoms of MS?

Applegate first noticed symptoms in 2019 while filming the pilot episode of Dead to Me. She experienced balance issues and unexpectedly fell during a scene, which she now recognizes as an early sign of MS.

2. How did the cast and crew of Dead to Me support Christina Applegate?

The cast and crew adapted scenes, adjusted schedules, and prioritized Applegate’s health, creating a supportive and accommodating work environment.

3. What are the symptoms of Multiple Sclerosis (MS)?

Common symptoms of MS include fatigue, balance problems, muscle weakness, pain, tingling, and coordination issues. Symptoms can vary in severity and progression.

4. Is Christina Applegate still acting?

Christina Applegate has retired from on-camera acting but remains open to voiceover roles. She continues to share her journey and advocate for MS awareness.

5. How has Christina Applegate coped with MS?

Applegate relies on her humor, support from loved ones, and a positive outlook to navigate the challenges of MS. She remains vocal about her experiences to inspire others.